After 22 years living in the suburbs, Greg and Kate move to Manhattan, and Greg finds a stray dog in the park with only a nametag: "Sylvia." Sylvia is street smart and quickly becomes a bone of contention between them. To Greg, Sylvia offers an escape from the frustrations of his job and the unknowns of middle age. To Kate, Sylvia becomes a rival for affection. The conflict between them leads to a series of hilarious and touching complications.